Research Article | | Peer-Reviewed

Epidemiological Trends Related to Stroke and Neuroinfectious Diseases in Patients Admitted to the Neurology Unit at Cocody Teaching Hospital in Abidjan

Received: 25 August 2024     Accepted: 13 September 2024     Published: 29 September 2024
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Abstract

Background: In Ivory Coast, as in many tropical regions, there is a significant coexistence of infectious diseases and non-communicable diseases (NCDs), particularly within the field of neurology. The dual burden of neuroinfectious diseases, including meningitis and strokes, plays a crucial role in shaping public health strategies implemented by the World Health Organization (WHO) and national health programs. Unfortunately, the epidemiological trends are not regularly updated. This study aims to provide insights into hospital admissions and mortality related to strokes and brain infections to inform health policies and improve disease management. Method: It was a retrospective study that examined the medical records of patients admitted to the neurology department of the Cocody University Hospital in Abidjan from January 1, 2020, to December 31, 2023, and included individuals across all age groups who were diagnosed with stroke, brain abscess, meningitis, or encephalitis. Results: The study involved 1,518 patients, strokes were more common among older adults, with an average age of 57.3 ± 13.7 years. Strokes represented the primary reason for hospitalization, making up 69% of cases, with an annual growth rate of approximately 2%, while neuroinfectious diseases accounted for 13% of total admissions. In-hospital mortality rates were 15% for stroke patients and 28% for those with neuroinfectious diseases, the latter showing a significantly higher mortality risk (odds ratio = 2.50; p < 0.001). Conclusion: Strokes are the leading cause of hospital admissions in our department, with increasing rates; however, neuroinfectious diseases have higher and stable mortality rates, indicating a more severe prognosis. Therefore, health policies must be reassessed to improve prevention and management for both diseases.

Published in European Journal of Preventive Medicine (Volume 12, Issue 5)
DOI 10.11648/j.ejpm.20241205.12
Page(s) 121-131
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Epidemiological Trends, Stroke, Neuroinfectious Disease, Abidjan, Tropical Region

References
[1] Wahdan MH. The epidemiological transition. EMHJ - Eastern Mediterranean Health Journal, 2 (1), 8-20, 1996. Published online 1996. Accessed August 25, 2024.
[2] GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021; 20(10): 795-820.
[3] Walker R, Whiting D, Unwin N, et al. Stroke incidence in rural and urban Tanzania: a prospective, community-based study. Lancet Neurol. 2010; 9(8): 786-792.
[4] Maredza M, Bertram MY, Tollman SM. Disease burden of stroke in rural South Africa: an estimate of incidence, mortality and disability adjusted life years. BMC Neurol. 2015; 15: 54.
[5] Lekoubou A, Nkoke C, Dzudie A, Kengne AP. Stroke admission and case-fatality in an urban medical unit in sub-Saharan Africa: a fourteen year trend study from 1999 to 2012. J Neurol Sci. 2015; 350(1-2): 24-32.
[6] Feigin VL, Vos T, Nichols E, et al. The global burden of neurological disorders: translating evidence into policy. Lancet Neurol. 2020; 19(3): 255-265.
[7] Rocklöv J, Dubrow R. Climate change: an enduring challenge for vector-borne disease prevention and control. Nat Immunol. 2020; 21(5): 479-483.
[8] Wahab KW. The burden of stroke in Nigeria. Int J Stroke. 2008; 3(4): 290-292.
[9] Institute of Medicine (US) Committee on Emerging Microbial Threats to Health in the 21st Century. Microbial Threats to Health: Emergence, Detection, and Response. (Smolinski MS, Hamburg MA, Lederberg J, eds.). National Academies Press (US); 2003. Accessed August 25, 2024.
[10] Desenclos JC, De Valk H. [Emergent infectious diseases: importance for public health, epidemiology, promoting factors, and prevention]. Med Mal Infect. 2005; 35(2): 49-61.
[11] Cowppli B, Sonan T, Akani F, Datie A. [Epidemiologie des patients hospitalisés en neurologie: experience du centre hospitalier universitaire de cocody à abidjan]. AJNS. [AJNS 2004 Vol. 23, No 2] Accessed March 27, 2024.
[12] B O Osuntokun, Stroke in the Africans. Afr J Med Med Sci 1977 Jun; 6(2): 39-53. Accessed August 25, 2024.
[13] Kim J, Thayabaranathan T, Donnan GA, et al. Global Stroke Statistics 2019. Int J Stroke. 2020; 15(8): 819-838.
[14] Connor MD, Walker R, Modi G, Warlow CP. Burden of stroke in black populations in sub-Saharan Africa. Lancet Neurol. 2007; 6(3): 269-278.
[15] Diarra ÉAA, Assouan AEK, Yao RB, Kouame LK, Kadjo C, Tanoh C. Épidémiologie des AVC en Côte d’Ivoire et perspectives. Revue Neurologique. 2016; 172: A164.
[16] Evelyne A, Zakaria M, Mohamed S, Berthe A. Profil épidémiologique et étiologique des méningo-encéphalites infectieuses observées dans le service de neurologie du CHU de Cocody (Abidjan). Revue Neurologique. 2015 ; 171 : A137.
[17] Barker DJ. The intrauterine origins of cardiovascular disease. Acta Paediatr Suppl. 1993; 82 Suppl 391: 93-99; discussion 100.
[18] D J Barker. The intrauterine environment and adult cardiovascular disease. Ciba Found Symp. 1991: 156: 3-10.
[19] Hult M, Tornhammar P, Ueda P, et al. Hypertension, diabetes and overweight: looming legacies of the Biafran famine. PLoS One. 2010; 5(10): e13582.
[20] Azarpazhooh MR, Hachinski V. Air pollution: A silent common killer for stroke and dementia. Int J Stroke. 2018; 13(7): 667-668.
[21] Wichmann J, Voyi K. Ambient air pollution exposure and respiratory, cardiovascular and cerebrovascular mortality in Cape Town, South Africa: 2001–2006. Int J Environ Res Public Health. 2012; 9(11): 3978-4016.
[22] Keates AK, Mocumbi AO, Ntsekhe M, Sliwa K, Stewart S. Cardiovascular disease in Africa: epidemiological profile and challenges. Nat Rev Cardiol. 2017; 14(5): 273-293.
[23] Knowledge of risk among patients at increased risk for stroke - PubMed. Accessed August 25, 2024.
[24] Akinyemi RO, Owolabi MO, Ihara M, et al. Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa. Brain Res Bull. 2019; 145: 97-108.
[25] Bennett JE, Stevens GA, Mathers CD, et al. NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4. The Lancet. 2018; 392(10152): 1072-1088.
[26] Bigna JJ, Noubiap JJ. The rising burden of non-communicable diseases in sub-Saharan Africa. The Lancet Global Health. 2019; 7(10): e1295-e1296.
[27] Maladies non transmissibles. Accessed August 25, 2024.
[28] Kabakambira JD, Bitwayiki RN, Mujawamariya G, Lucero-Prisno III DE& M. Kigali Car Free Day: An Innovative Model in the Fight against Non-Communicable Disease Pandemics. Rwanda Medical Journal. 76(3): 1-5.
[29] Glazener A, Wylie J, van Waas W, Khreis H. The Impacts of Car-Free Days and Events on the Environment and Human Health. Curr Envir Health Rpt. 2022; 9(2): 165-182.
[30] O’Donnell MJ, Chin SL, Rangarajan S, et al. Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study. Lancet. 2016; 388(10046): 761-775.
[31] Okekunle AP, Jones S, Adeniji O, et al. Stroke in Africa: A systematic review and meta-analysis of the incidence and case-fatality rates. Int J Stroke. 2023; 18(6): 634-644.
[32] Seminog OO, Scarborough P, Wright FL, Rayner M, Goldacre MJ. Determinants of the decline in mortality from acute stroke in England: linked national database study of 795 869 adults. BMJ. 2019; 365: l1778.
[33] Ouendo EM, Makoutodé M, Paraiso MN, Wilmet-Dramaix M, Dujardin B. Itinéraire thérapeutique des malades indigents au Bénin (Pauvreté et soins de santé). Tropical Medicine & International Health. 2005; 10(2): 179-186.
[34] Caselli G. The key phases of the European health transition. Pol Popul Rev. 1995; (7): 73-102.
[35] Frenk J, Bobadilla JL, Stern C, Frejka T, Lozano R. Elements for a theory of the health transition. Health Transit Rev. 1991; 1(1): 21-38.
[36] Olshansky SJ, Ault AB. The fourth stage of the epidemiologic transition: the age of delayed degenerative diseases. Milbank Q. 1986; 64(3): 355-391.
[37] Berkowitz AL, Raibagkar P, Pritt BS, Mateen FJ. Neurologic manifestations of the neglected tropical diseases. Journal of the Neurological Sciences. 2015; 349(1): 20-32.
Cite This Article
  • APA Style

    Magala, G. C., Tanoh, M. A., Tanoh, A. C., Kadjo, C. V., Magala, J. B., et al. (2024). Epidemiological Trends Related to Stroke and Neuroinfectious Diseases in Patients Admitted to the Neurology Unit at Cocody Teaching Hospital in Abidjan. European Journal of Preventive Medicine, 12(5), 121-131. https://doi.org/10.11648/j.ejpm.20241205.12

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    ACS Style

    Magala, G. C.; Tanoh, M. A.; Tanoh, A. C.; Kadjo, C. V.; Magala, J. B., et al. Epidemiological Trends Related to Stroke and Neuroinfectious Diseases in Patients Admitted to the Neurology Unit at Cocody Teaching Hospital in Abidjan. Eur. J. Prev. Med. 2024, 12(5), 121-131. doi: 10.11648/j.ejpm.20241205.12

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    AMA Style

    Magala GC, Tanoh MA, Tanoh AC, Kadjo CV, Magala JB, et al. Epidemiological Trends Related to Stroke and Neuroinfectious Diseases in Patients Admitted to the Neurology Unit at Cocody Teaching Hospital in Abidjan. Eur J Prev Med. 2024;12(5):121-131. doi: 10.11648/j.ejpm.20241205.12

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  • @article{10.11648/j.ejpm.20241205.12,
      author = {Gloire Chubaka Magala and Muriel Amon Tanoh and Abel Christian Tanoh and Cedric Valery Kadjo and Jonathan Bachiseze Magala and Fiacre Delors Offoumou and Desirée Aka Arlette and Constance Yapo Ehounoud and Nancy Tania Essoin-De Souza and Yves Broh N’guessan and Mavouloh Kourouma and Evelyne Aka-Anghui Diarra and Berthe Assi},
      title = {Epidemiological Trends Related to Stroke and Neuroinfectious Diseases in Patients Admitted to the Neurology Unit at Cocody Teaching Hospital in Abidjan
    },
      journal = {European Journal of Preventive Medicine},
      volume = {12},
      number = {5},
      pages = {121-131},
      doi = {10.11648/j.ejpm.20241205.12},
      url = {https://doi.org/10.11648/j.ejpm.20241205.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20241205.12},
      abstract = {Background: In Ivory Coast, as in many tropical regions, there is a significant coexistence of infectious diseases and non-communicable diseases (NCDs), particularly within the field of neurology. The dual burden of neuroinfectious diseases, including meningitis and strokes, plays a crucial role in shaping public health strategies implemented by the World Health Organization (WHO) and national health programs. Unfortunately, the epidemiological trends are not regularly updated. This study aims to provide insights into hospital admissions and mortality related to strokes and brain infections to inform health policies and improve disease management. Method: It was a retrospective study that examined the medical records of patients admitted to the neurology department of the Cocody University Hospital in Abidjan from January 1, 2020, to December 31, 2023, and included individuals across all age groups who were diagnosed with stroke, brain abscess, meningitis, or encephalitis. Results: The study involved 1,518 patients, strokes were more common among older adults, with an average age of 57.3 ± 13.7 years. Strokes represented the primary reason for hospitalization, making up 69% of cases, with an annual growth rate of approximately 2%, while neuroinfectious diseases accounted for 13% of total admissions. In-hospital mortality rates were 15% for stroke patients and 28% for those with neuroinfectious diseases, the latter showing a significantly higher mortality risk (odds ratio = 2.50; p < 0.001). Conclusion: Strokes are the leading cause of hospital admissions in our department, with increasing rates; however, neuroinfectious diseases have higher and stable mortality rates, indicating a more severe prognosis. Therefore, health policies must be reassessed to improve prevention and management for both diseases.
    },
     year = {2024}
    }
    

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  • TY  - JOUR
    T1  - Epidemiological Trends Related to Stroke and Neuroinfectious Diseases in Patients Admitted to the Neurology Unit at Cocody Teaching Hospital in Abidjan
    
    AU  - Gloire Chubaka Magala
    AU  - Muriel Amon Tanoh
    AU  - Abel Christian Tanoh
    AU  - Cedric Valery Kadjo
    AU  - Jonathan Bachiseze Magala
    AU  - Fiacre Delors Offoumou
    AU  - Desirée Aka Arlette
    AU  - Constance Yapo Ehounoud
    AU  - Nancy Tania Essoin-De Souza
    AU  - Yves Broh N’guessan
    AU  - Mavouloh Kourouma
    AU  - Evelyne Aka-Anghui Diarra
    AU  - Berthe Assi
    Y1  - 2024/09/29
    PY  - 2024
    N1  - https://doi.org/10.11648/j.ejpm.20241205.12
    DO  - 10.11648/j.ejpm.20241205.12
    T2  - European Journal of Preventive Medicine
    JF  - European Journal of Preventive Medicine
    JO  - European Journal of Preventive Medicine
    SP  - 121
    EP  - 131
    PB  - Science Publishing Group
    SN  - 2330-8230
    UR  - https://doi.org/10.11648/j.ejpm.20241205.12
    AB  - Background: In Ivory Coast, as in many tropical regions, there is a significant coexistence of infectious diseases and non-communicable diseases (NCDs), particularly within the field of neurology. The dual burden of neuroinfectious diseases, including meningitis and strokes, plays a crucial role in shaping public health strategies implemented by the World Health Organization (WHO) and national health programs. Unfortunately, the epidemiological trends are not regularly updated. This study aims to provide insights into hospital admissions and mortality related to strokes and brain infections to inform health policies and improve disease management. Method: It was a retrospective study that examined the medical records of patients admitted to the neurology department of the Cocody University Hospital in Abidjan from January 1, 2020, to December 31, 2023, and included individuals across all age groups who were diagnosed with stroke, brain abscess, meningitis, or encephalitis. Results: The study involved 1,518 patients, strokes were more common among older adults, with an average age of 57.3 ± 13.7 years. Strokes represented the primary reason for hospitalization, making up 69% of cases, with an annual growth rate of approximately 2%, while neuroinfectious diseases accounted for 13% of total admissions. In-hospital mortality rates were 15% for stroke patients and 28% for those with neuroinfectious diseases, the latter showing a significantly higher mortality risk (odds ratio = 2.50; p < 0.001). Conclusion: Strokes are the leading cause of hospital admissions in our department, with increasing rates; however, neuroinfectious diseases have higher and stable mortality rates, indicating a more severe prognosis. Therefore, health policies must be reassessed to improve prevention and management for both diseases.
    
    VL  - 12
    IS  - 5
    ER  - 

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Author Information
  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Internal Medicine Department, Evangelical University in Africa, Bukavu, Democratic Republic of Congo

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

  • Biosciences Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

  • Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast; Neurology Department, Treichville University Hospital, Abidjan, Ivory Coast

  • Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast; Neurology Department, Treichville University Hospital, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

  • Neurology Department, Cocody University Hospital, Abidjan, Ivory Coast; Nervous System and Rehabilitation Department, Felix Houphouët-Boigny University, Abidjan, Ivory Coast

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